Månsson S, Ekberg O, Ohlsson B. Motility index measured by magnetic resonance enterography is associated with sex and mural thickness. World J Gastroenterol 2020; 26(36): 5484-5497 [PMID: 33024399 DOI: 10.3748/wjg.v26.i36.5484]
Corresponding Author of This Article
Bodil Ohlsson, MD, PhD, Professor, Department of Internal Medicine, Skåne University Hospital, Lund University, Jan Waldenströms Street 15, Malmö S-205 02, Sweden. bodil.ohlsson@med.lu.se
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Sep 28, 2020; 26(36): 5484-5497 Published online Sep 28, 2020. doi: 10.3748/wjg.v26.i36.5484
Table 1 True fast imaging with steady precession acquisition parameters
Parameters
Values
Repetition time
3.26 ms
Echo time
1.63 ms
Pixel size
2.5 mm × 1.8 mm
Slice thickness
8 mm
Flip angle
50 degrees
Parallel imaging acceleration
2
Number of averages
1
Number of frames
50
Time between frames
409 ms
Duration of acquisition
21 s
Table 2 Basic characteristics and symptoms in controls and disease groups
Controls, n = 22
Crohn’s disease, n = 134
IBS, n = 34
Ulcerative colitis, n = 15
Other, n = 15
Dysmotility, n = 4
P value
Men/women
12 (54.5)/10
75 (56.0)/59
8 (23.5)/26
8 (53.3)/7
13 (86.7)/2
1 (25.0)/3
0.001
(45.5)
(44.0)
(76.5)
(46.7)
(13.3)
(75.0)
Age (yr)
30 (25-52)
35 (28-48)
34 (24-44)
35 (25-44)
45 (30-67)
43 (37-63)
0.130
Weight (kg)
65 (55-89)
73 (61-85)
70 (55-84)
79 (54-90)
76 (66-93)
66 (64-70)
0.639
Missing value
2
4
9
5
2
Abdominal pain
0 (0-0)
25 (0-51)
71 (54-82)
0 (0-35)
66 (24-80)
80 (16-99)
< 0.001
Days of pain
0 (0-0)
29 (0-71)
61 (23-100)
21(0-21)
36 (7-100)
50 (0-
< 0.001
Diarrhea
3 (0-14)
41 (8-70)
54 (20-76)
43 (22-51)
50 (10-67)
42 (2-90)
0.003
Constipation
5 (0-14)
12 (0-46)
37 (4-62)
20 (0-52)
50 (7-68)
90 (74-96)
0.002
Bloating
0 (0-7)
22 (0-47)
51 (26-63)
0 (0-38)
0 (0-46)
82 (18-99)
< 0.001
Vomiting and Nausea
2 (0-16)
6 (0-25)
25 (2-65)
0 (0-8)
18 (3-49)
75 (65-95)
< 0.001
Flatulence
6 (0-26)
46 (25-68)
63 (48-89)
23 (8-54)
21 (5-73)
76 (66-94)
< 0.001
Satisfaction with bowel habits
10 (7-20)
50 (22-76)
54 (28-80)
44 (13-57)
62 (18-71)
86 (63-100)
< 0.001
Influence on daily life
5 (0-15)
51 (25-75)
77 (58-88)
50 (36-60)
49 (22-66)
100 (80-100)
< 0.001
Psychological well-being
8 (5-17)
36 (14-77)
48 (20-71)
7 (2-42)
52 (5-76)
100 (94-
< 0.001
Total IBS-SSS
16 (10-72)
172 (88-301)
317 (234-351)
157 (114-194)
182 (90-313)
318 (146-
< 0.001
Missing value
6
69
7
10
10
2
Table 3 Motility index in different groups and stratified for sex
Controls, n = 22
Crohn’s disease, n = 134
IBS, n = 34
Ulcerative colitis, n = 15
Other, n = 15
Dysmotility, n = 4
P valueANOVA
Jejunum
0.36 ± 0.08
0.32 ± 0.09
0.33 ± 0.07
0.30 ± 0.10
0.27 ± 0.07
0.39 ± 0.07
0.021
Missing
1
1
0
0
2
0
Men
0.34 ± 0.10
0.34 ± 0.08
0.35 ± 0.08
0.29 ± 0.09
0.27 ± 0.08
0.39 ± -#-
Women
0.37 ± 0.05
0.31 ± 0.09
0.33 ± 0.06
0.30 ± 0.12
0.28 ± 0.06
0.39 ± 0.09
P value sex
0.405
0.085
0.365
0.761
0.778
0.957
Ileum
0.42 ± 0.06
0.38 ± 0.09
0.40 ± 0.06
0.38 ± 0.09
0.36 ± 0.08
0.39 ± 0.03
0.200
Missing
1
1
0
0
2
0
Men
0.43 ± 0.54
0.38 ± 0.09
0.37 ± 0.05
0.38 ± 0.11
0.36 ± 0.08
0.36 ± -#-
Women
0.42 ± 0.06
0.37 ± 0.09
0.40 ± 0.07
0.38 ± 0.06
0.41 ± 0.01
0.40 ± 0.03
P value sex
0.898
0.487
0.251
0.940
0.399
0.384
Terminal ileum
0.34 ± 0.10
0.27 ± 0.11
0.32 ± 0.09
0.32 ± 0.08
0.22 ± 0.05
0.34 ± 0.02
0.007
Missing
3
19
2
4
5
0
Men
0.31 ± 0.09
0.26 ± 0.11
0.27 ± 0.07
0.35 ± 0.09
0.22 ± 0.05
0.36 ± -#-
Women
0.38 ± 0.12
0.29 ± 0.11
0.33 ± 0.10
0.29 ± 0.07
0.25 ± -#-
0.34 ± 0.03
P value sex
0.180
0.241
0.110
0.270
0.637
0.645
Table 4 Basic characteristics in men and women
Women, n = 107
Men, n = 117
P value
Age (yr)
37.00 (27.00-47.00)
35.00 (27.50-50.00)
0.353
Weight (kg)
66.88 ± 16.84
79.93 ± 17.04
< 0.001
Missing value
18
17
Mural thickness (mm)
Jejunum
2 (2-2)
2 (2-2)
0.135
Missing value
2
Ileum Missing value
2 (2-2)
2 (2-2) 2
0.031
Terminal ileum
2 (2-2)
2 (2-4.5)
0.044
Missing value
5
4
Motility index (au)
Jejunum
0.32 ± 0.08
0.33 ± 0.08
0.542
Missing value
1
3
Ileum
0.39 ± 0.08
0.38 ± 0.08
0.808
Missing value
1
3
Terminal ileum
0.31 ± 0.11
0.27 ± 0.10
0.013
Missing value
16
7
Citation: Månsson S, Ekberg O, Ohlsson B. Motility index measured by magnetic resonance enterography is associated with sex and mural thickness. World J Gastroenterol 2020; 26(36): 5484-5497