Observational Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2020; 26(36): 5484-5497
Published online Sep 28, 2020. doi: 10.3748/wjg.v26.i36.5484
Motility index measured by magnetic resonance enterography is associated with sex and mural thickness
Sven Månsson, Olle Ekberg, Bodil Ohlsson
Sven Månsson, Medical Radiation Physics, Department of Translational Medicine, Lund University, Skåne University Hospital Malmö, Malmö 20502, Sweden
Olle Ekberg, Department of Translational Medicine, Diagnostic Radiology, Lund University, Skåne University Hospital, Malmö 20502, Sweden
Bodil Ohlsson, Department of Internal Medicine, Skåne University Hospital, Lund University, Malmö S-205 02, Sweden
Author contributions: Ekberg O, Månsson S and Ohlsson B designed and performed the research study; Ekberg O, Månsson S and Ohlsson B analyzed the data; Ohlsson B wrote the initial draft of the paper; all authors contributed to the intellectual process during the writing and finalization of the manuscript.
Supported by the Development Foundation of Region Skåne, No. REGSKANE-619091; the Foundation of Skåne University Hospital, No. 2017-008; and the Dir Albert Påhlsson’s Foundation, No. 2019.
Institutional review board statement: This study was performed in accordance with the Helsinki Declaration and approved by the Ethics Review Board at Lund University (No 2016/330, date of approval 4 August 2016). All patients and healthy volunteers gave their written informed consent before inclusion.
Conflict-of-interest statement: There are no conflicts of interest for any of the authors.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at email adress bodil.ohlsson@med.lu.se.
STROBE statement: The guidelines of the STROBE Statement have been adopted.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Bodil Ohlsson, MD, PhD, Professor, Department of Internal Medicine, Skåne University Hospital, Lund University, Jan Waldenströms Street 15, Malmö S-205 02, Sweden. bodil.ohlsson@med.lu.se
Received: June 12, 2020
Peer-review started: June 12, 2020
First decision: July 25, 2020
Revised: July 27, 2020
Accepted: September 4, 2020
Article in press: September 4, 2020
Published online: September 28, 2020
Core Tip

Core Tip: Motility index (MI) of the terminal ileum measured by magnetic resonance enterography (MRE) was inversely associated with mural thickness, especially in men. The tendency of lower MI in men than in women, could possibly be explained by higher weight in men. In women, diarrhea was inversely associated with MI of jejunum, and constipation was positively associated with MI of terminal ileum. There were differences in MI of jejunum and terminal ileum between healthy controls and other assorted diseases. MIs in the jejunum and ileum revealed few findings. It seems essential to develop additional techniques to identify true motility patterns according to MRE.