Clinical significance of changes in the Th17/Treg ratio in autoimmune liver disease

Table 1 Liver function in group E

Liver function	Subgroup EA (n = 31)	Subgroup ER (n = 11)	P value
TBIL (μmol/L)	133.10 (55.00, 200.20)	17.60 (12.10, 24.90)	< 0.001
DBIL (μmol/L)	87.20 (38.80, 151.10)	7.60 (6.20, 15.80)	< 0.001
ALT (U/L)	116.00 (47.00, 314.00)	28.00 (10.00, 56.00)	< 0.001
AST (U/L)	103.00 (76.00, 343.00)	37.00 (30.00, 51.00)	< 0.001
ALP (U/L)	128.00 (113.00, 173.00)	74.00 (51.00, 110.00)	0.001
γ-GT (U/L)	160.50 (99.75, 281.00)	34.00 (16.00, 44.00)	< 0.001
GLB (g/L)	29.69 ± 5.70	28.89 ± 4.35	0.678

TBIL: Total bilirubin; DBIL: Direct bilirubin; ALT: Glutamic-pyruvic transaminase; AST: Glutamic-oxaloacetic transaminase; ALP: Alkaline phosphatase; γ-GT: γ-glutamyl transferase.

Table 2 On-admission liver function of the patients with different outcomes in group EA

Liver function	Unhealed group (n = 12)	Improved group (n = 19)	P value
TBIL (μmol/L)	166.75 (112.70, 244.30)	103.10 (46.90, 175.20)	0.114
DBIL (μmol/L)	122.0 (80.20, 122.00)	70.30 (28.80, 121.00)	0.059
ALT (U/L)	57.50 (44.00, 106.50)	195.00 (104.00, 724.00)	0.002
AST (U/L)	86.00 (53.50, 94.75)	151.00 (103.00, 513.00)	0.001
ALP (U/L)	153.00 (115.00, 405.00)	121.50 (95.50, 151.25)	0.089
γGGT (U/L)	259.00 (144.50, 370.00)	133.00 (69.75, 253.50)	0.072
GLB (g/L)	30.16 ± 6.27	29.48 ± 5.42	0.756

TBIL: Total bilirubin; DBIL: Direct bilirubin; ALT: Glutamic-pyruvic transaminase; AST: Glutamic-oxaloacetic transaminase; ALP: Alkaline phosphatase; γ-GT: γ-glutamyl transferase.

Table 3 Expressions of Th17, Treg, Th1, and Th2 in the three groups

	Th17 (%)	Treg (%)	Th17/Treg
EA (n = 31)	0.79 (0.48, 1.20)1	2.91 ± 1.081	0.31 (0.18, 0.46)1
ER (n = 11)	0.29 (0.22, 0.78)	3.38 ± 1.16	0.14 (0.07, 0.19)1
C (n = 11)	0.27 ± 0.19	4.75 ± 2.45	0.07 (0.03, 0.09)

¹Statistically significant difference when compared with group C.