Laparoscopic fenestration vs open fenestration in patients with congenital hepatic cysts: A meta-analysis

Table 1 General characteristics of the included studies

Included studies	Design types	Patients		Age (yr)		Gender (M/F)		Site (left/right/bilobar)		Cyst size (cm)		Cyst types (single/multiple/polycystic)		Main complaints	Measured outcomes
		OF	LF	OF	LF	OF	LF	OF	LF	OF	LF	OF	LF
Yi et al[11]	N-RCT	117	52	45 ± 12.8	43 ± 9.2	43/74	21/32	21/58/ND	16/22/ 0	9.5 ± 3.4	8.9 ± 4.6	79/38/ 37	38/14/ 11	A, B, C, D	1-4, 6, 9
Felizardo et al[12]	N-RCT	34	37	52.6 ± 21.8	51.1 ± 20.3	13/21	17/20	05/17/ 12	04/16/ 17	12.8 ± 6.3	114 ± 6.7	20/14/ND	19/18/ND	A, B, C, D	1-3, 4, 8
Chen et al[13]	N-RCT	19	17	44.2	41.1	23/13		ND	ND	ND	ND	ND	ND	A, B, C, D	1, 2, 3, 7
Qiu et al[14]	N-RCT	29	22	ND	ND	22/29		ND	ND	ND	ND	ND	ND	A, B, C, D	1-5, 7
Li et al[15]	N-RCT	40	46	18-83 (45)		ND		ND	ND	ND	ND	ND	ND	A, B, C, D	3, 4, 5
Guo et al[16]	N-RCT	27	31	42 ± 11.2	45 ± 9.8	09/18	12/19	08/11/ND	09/13/ND	8.4 ± 4.7	9.9 ± 5.8	19/18/ 21	09/09/ 09	A, B, C	1-3, 6, 7
Mazza et al[17]	N-RCT	37	66	19-87 (62.5)		ND		ND	ND	ND	ND	24/13/ND	46/20/ND	A, B, C, D	3, 4, 5
Gigot et al[18]	N-RCT	5	19	45	57	05/0	18/01	01/04/0	12/05/02	7-17 (10)	8-30 (13)	03/02/0	10/06/03	A, B, C, D	3, 4
Treckmann et al[19]	N-RCT	17	42	28-86 (62)		07/52		05/08/04	25/09/08	6-20 (11.2)	6-18 (10.8)	11/03/ND	38/04/ND	A, B, C, D	1, 4, 5

OF: Open fenestration group; LF: Laparoscopic fenestration group; A: Abdominal pain; B: Abdominal distension; C: Nnausea; D: Vomiting; ND: Not mentioned; RCT: Randomized controlled trial; 1: Operative time; 2: Intraoperative blood loss; 3: Hospital stay; 4: Incidence of postoperative complications; 5: The time to return to normal diet; 6: The time to return to normal activities; 7: Hospitalization cost; 8: The recovery time of liver functions; 9: The recurrence rates of symptoms.

Table 2 Summary of the methodological quality of all included studies

Included studies	Allocation method	Homogeneity analysis	Identification of prognostic factors	Control of bias
Yi et al[11]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Age, sex, cyst location, types, size	No
Felizardo et al[12]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Age cyst location, size, type	No
Chen et al[13]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Age, sex, clinical complaints	No
Qiu et al[14]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Sex, main clinical complaints	No
Li et al[15]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Age, cyst location, type, size	No
Guo et al[16]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Age, sex, cyst location, type, size	No
Mazza et al[17]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Reported the age, cyst type, main complaints	No
Gigot et al[18]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Age, sex, cyst location, type, size	No
Treckmann et al[19]	By doctors and patients	All the included cases come from the same research center, with good homogeneity	Age, sex, cyst location , type, size	No