Brief Article
Copyright ©2010 Baishideng.
World J Gastroenterol. Jul 28, 2010; 16(28): 3541-3545
Published online Jul 28, 2010. doi: 10.3748/wjg.v16.i28.3541
Table 1 Relation between serum ferritin concentrations and cataracts
Family memberSerum ferritin (μg/L)Transferrin saturation (%)Cataract
A I 1154218Yes
A I 2158117Yes
A II 1204922Yes
A II 498817Yes
A II 5185526Yes
A III 190237Yes
A II 23721No
A II 349NANo
A III 21516No
A III 319NANo
B I 1NANAYes
B I 2NANANo
B II 121439Yes
B II 2NANAYes
B II 3112837Yes
Table 2 Demographic and biochemical results for healthy controls and hereditary hyperferritinemia cataract syndrome patients (mean ± SD)
Healthy controlsHHCS cohortReference values
No. (M:F)25 (11:14)6 (1:5)
Age (range), yr36 (21-62)44.65 (21-75)
Hb (g/dL)13.8 ± 1.312.8 ± 2.313-17
MCV (fL)87.8 ± 5.890.4 ± 3.680-100
Iron (μmol/L)16.4 ± 4.015.6 ± 6.710.6-28.3
Ferritin (μg/L)  110 ± 128 1716.3 ± 37630-400
Prohepcidin (ng/mL)236.88 ± 83.68187 ± 120.9NA
Hepcidin (ng/mL)15.68 ± 15.719.1 ± 18.6NA
TIBC (μmol/L)59.2 ± 9.670.67 ± 19.941-77
Tsat %28.8 ± 9.621.5 ± 9.5NA
Vitamin B12 (pg/mL) 280.4 ± 153324.2 ± 127.2180-914
Serum folate (ng/mL) 8.2 ± 4.0 5.5 ± 1.93.1-17.5
Bilirubin (μmol/L) 10.44 ± 5.5 5.3 ± 30-20
ALP (IU/L) 73.3 ± 26.6 77.5 ± 1140-129
ALT (IU/L) 30.3 ± 22.417.7 ± 6.910-50
Albumin (g/L)46.2 ± 2.442.7 ± 4.234-50