Study on P53 protein and C-erbB2 protein expression in primary hepatic cancer and colorectal cancer by flow cytometry

doi:10.3748/wjg.v4.iSuppl2.102

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 1998; 4(Suppl2): 102-102
Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.102

Study on P53 protein and C-erbB2 protein expression in primary hepatic cancer and colorectal cancer by flow cytometry

Feng Luo, Bing Kan, Song Lei, Lu-Nan Yan, Yong-Qiu Mao, Li-Qun Zou, Yan-Xia Yang, Yu-Quan Wei

Feng Luo, Bing Kan, Song Lei, Lu-Nan Yan, Yong-Qiu Mao, Li-Qun Zou, Yan-Xia Yang, Yu-Quan Wei, The Center of Biotherapy for Cancer, First Hospital West China University of Medical Sciences, Chengdu 610041, Sichuan Province, China

Author contributions: All authors contributed equally to the work.

Correspondence to: Dr. Feng Luo, The Center of Biotherapy for Cancer, First Hospital West China University of Medical Sciences, Chengdu 610041, Sichuan Province, China

Received: June 27, 1998
Revised: August 6, 1998
Accepted: August 28, 1998
Published online: October 15, 1998

Abstract

AIM: Quantitative study on P53 protein and C-erbB2 protein in primary hepatic cancer and colorectal cancer.

METHODS: The expression of P53 protein and C-erbB2 protein was quantitatively detected using flow cytometry in 15 primary hepatic cancer and 22 colorectal cancer.

RESULTS: The positive expression rates and the average expression of P53 protein and C-erbB2 protein in primary hepatic cancer were 26.6%, 0.69FI, 20%, 0.73FI, respectively. The positive expression rates and the aver age expression of P53 protein and C-erbB2 protein in colorectal cancer were 36.3%, 0.86FI, 31.8%, 0.71FI, respectively. The percentage of positive expression rates of cancer cells were different from one case to another.

CONCLUSION: The quantitative study method on P53 protein and C-erbB2 protein expression in primary hepatic cancer and colorectal cancer by flow cytometry was established. Flow cytometry is a new procedure by which we can quantitatively analyse the expression of P53 protein and C-erbB2 protein in hepatic and colorectal cancer.

Key Words: Liver neoplasms, Colorectal neoplasms, P53 protein, C-erbB2 protein, Flow cytometry

Citation: Luo F, Kan B, Lei S, Yan LN, Mao YQ, Zou LQ, Yang YX, Wei YQ. Study on P53 protein and C-erbB2 protein expression in primary hepatic cancer and colorectal cancer by flow cytometry. World J Gastroenterol 1998; 4(Suppl2): 102-102
URL: https://www.wjgnet.com/1007-9327/full/v4/iSuppl2/102.htm
DOI: https://dx.doi.org/10.3748/wjg.v4.iSuppl2.102

Footnotes

E- Editor: Li RF