Published online Oct 15, 1998. doi: 10.3748/wjg.v4.iSuppl2.102
Revised: August 6, 1998
Accepted: August 28, 1998
Published online: October 15, 1998
AIM: Quantitative study on P53 protein and C-erbB2 protein in primary hepatic cancer and colorectal cancer.
METHODS: The expression of P53 protein and C-erbB2 protein was quantitatively detected using flow cytometry in 15 primary hepatic cancer and 22 colorectal cancer.
RESULTS: The positive expression rates and the average expression of P53 protein and C-erbB2 protein in primary hepatic cancer were 26.6%, 0.69FI, 20%, 0.73FI, respectively. The positive expression rates and the aver age expression of P53 protein and C-erbB2 protein in colorectal cancer were 36.3%, 0.86FI, 31.8%, 0.71FI, respectively. The percentage of positive expression rates of cancer cells were different from one case to another.
CONCLUSION: The quantitative study method on P53 protein and C-erbB2 protein expression in primary hepatic cancer and colorectal cancer by flow cytometry was established. Flow cytometry is a new procedure by which we can quantitatively analyse the expression of P53 protein and C-erbB2 protein in hepatic and colorectal cancer.