Hong-Bo Shi, Hong-Lin Shi, Feng Ren, Zhong-Ping Duan, Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China
Jin-Li Lou, Clinical Laboratory Center, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China
Yu Chen, Zhong-Ping Duan, Artificial Liver Center, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China
Author contributions: Shi HB and Lou JL contributed equally to this work; Shi HB and Shi HL carried out most of the experiments; Ren F purified the strain and performed PCR; Chen Y analyzed the pattern of restriction enzyme digestion; Shi HB drafted the manuscript, and Lou JL analyzed the experimental data; Duan ZP and Lou JL conceived and supervised the study; Duan ZP was involved in editing the manuscript; all authors read and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 81300349 and No. 81270532; the Beijing Natural Science Foundation, No. 7144216; the Beijing Nova Program, No. Z131107000413016; the Project of Science and Technology Activities of Preferred Overseas Personnel of Beijing (2014); the Project of Cultivation of High Level Medical Technical Personnel in the Health System of Beijing, No. 2014-3-090 and No. 2013-3-071; Beijing Municipal Institute of public medical research development and reform pilot project, No. 2016-2.
Conflict-of-interest statement: Shi HB, Lou JL, Shi HL, Ren F, Chen Y and Duan ZP are employees of Beijing Youan Hospital, Capital Medical University. The authors declare no conflicts of interest.
Data sharing statement: Technical appendices, statistical codes and datasets are available from the corresponding author at firstname.lastname@example.org. Participants provided informed consent for data sharing. No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Zhong-Ping Duan, MD, PhD, Professor, Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, 8 Xitoutiao, Youwai Street, Fengtai District, Beijing 100069, China. email@example.com
Telephone: +86-10-63291007 Fax: +86-10-63295258
Received: August 2, 2016
Peer-review started: August 3, 2016
First decision: September 21, 2016
Revised: October 5, 2016
Accepted: November 2, 2016
Article in press: November 2, 2016
Published online: January 14, 2017