Yuichi Matsuo, Yasutoshi Kido, Junko Akada, Seiji Shiota, Tran Thanh Binh, Tran Thi Huyen Trang, Yoshio Yamaoka, Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan
Seiji Shiota, Department of General Medicine, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan
Tran Thanh Binh, Pham Huu Tung, Tran Dinh Tri, Ngo P Minh Thuan, Ho DQ Dung, Department of Endoscopy, Cho Ray Hospital, Hochiminh 800010, Vietnam
Tran Thi Huyen Trang, Department of Molecular Biology, 108 Military Central Hospital, Hanoi 100083, Vietnam
Le Quang Tam, Department of Endoscopy, Daklak Hospital, Daklak 55000, Vietnam
Bui Chi Nam, Department of Endoscopy, Lao Cai Hospital, Lao Cai 19000, Vietnam
Vu Van Khien, Department of Hepatogastroentrology, 108 Military Center Hospital, Hanoi 19000, Vietnam
Yoshio Yamaoka, Department of Medicine-Gastroenterology, Baylor College of Medicine and Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, United States
Author contributions: Matsuo Y, Kido Y, Akada J, Shiota S and Yamaoka Y conceived and designed the experiments; Matsuo Y, Kido Y, Akada J, Binh TT and Trang TTH performed the experiments; Binh TT, Dung HDQ, Tung PH, Tri TD, Thuan NPM, Tam LQ, Nam BC and Khien VV contributed to obtaining the samples; Matsuo Y, Kido Y, Akada J and Yamaoka Y contributed to analysis and interpretation; Matsuo Y, Kido Y, Akada J and Yamaoka Y drafted the manuscript.
Supported by the National Institutes of Health, No. DK62813; Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (in part), No. 25293104, No. 26640114 and No. 15H02657); the Japan Society for the Promotion of Science Institutional Program for Young Researcher Overseas Visits and the Strategic Funds for the Promotion of Science and Technology from the Japan Science and Technology Agency.
Institutional review board statement: Ethical approval was obtained from the Ethics Committees of Daklak Hospital and Lao Cai Hospital, Vietnam and the Oita University Faculty of Medicine, Japan.
Conflict-of-interest statement: No conflicts of interest exist.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yamaoka Yoshio, MD, PhD, Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, Oita 879-5593, Japan. email@example.com
Telephone: +81-97-5865740 Fax: +81-97-5865749
Received: August 15, 2016
Peer-review started: August 16, 2016
First decision: September 20, 2016
Revised: October 3, 2016
Accepted: October 27, 2016
Article in press: October 27, 2016
Published online: January 7, 2017