Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients

doi:10.3748/wjg.v23.i21.3864

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2017; 23(21): 3864-3875
Published online Jun 7, 2017. doi: 10.3748/wjg.v23.i21.3864

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Figure 1 Differential serum miRNA expression levels in non-infected healthy controls compared to hepatocellular carcinoma patients.

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Figure 2 Efficacy of studied miRNAs in hepatocellular carcinoma non-malignant differentiation using receiver operating characteristics curve analysis. Hepatocellular carcinoma (HCC) (n = 224) and healthy control (n = 84).

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Figure 3 Efficacy of studied miRNAs in hepatocellular carcinoma, hepatitis C virus categorization using receiver operating characteristics curve analysis. Hepatocellular carcinoma (n = 224) and hepatitis C virus (n = 250). AUC: Area under the curve.

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Figure 4 Diagnostic activity of the panel of miRNAs studied.

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Figure 5 Comparison between miRNA panel and alpha-fetoprotein using receiver operating characteristic curve. AFP: Alpha-fetoprotein; HCC: Hepatocellular carcinoma.

Citation: Elemeery MN, Badr AN, Mohamed MA, Ghareeb DA. Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients. World J Gastroenterol 2017; 23(21): 3864-3875
URL: https://www.wjgnet.com/1007-9327/full/v23/i21/3864.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i21.3864