Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2021; 27(19): 2366-2375
Published online May 21, 2021. doi: 10.3748/wjg.v27.i19.2366
Changes in the nutritional status of nine vitamins in patients with esophageal cancer during chemotherapy
Lan-Qing Liang, Ling-Ling Meng, Bo-Ning Cai, Ze-Ping Cui, Na Ma, Le-Hui Du, Wei Yu, Bao-Lin Qu, Sheng-Qiang Feng, Fang Liu
Lan-Qing Liang, Ling-Ling Meng, Bo-Ning Cai, Ze-Ping Cui, Na Ma, Le-Hui Du, Wei Yu, Bao-Lin Qu, Fang Liu, Department of Radiotherapy, Chinese PLA General Hospital, Beijing 100853, China
Sheng-Qiang Feng, Department of Health Service, The Guard Bureau of Joint Staff Department of Chinese PLA, Beijing 100017, China
Author contributions: Liang LQ and Meng LL contributed equally to this work; Liang LQ and Meng LL designed and performed the research and wrote the paper; Liu F designed the research and supervised the report; Cui ZP and Ma N designed the research and contributed to the analysis; Du LH, Yu W and Feng SQ provided clinical advice; Qu BL and Cai BN supervised the report.
Supported by Health Bureau of the Department of Logistics and Security of the Central Military Commission of China, No. 17BJZ47.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of the General Hospital of the Chinese People’s Liberation Army, No. S2019-198-02.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors hereby declare that there is no personal conflict of interest that may cause impact or bias to the results of this study. All authors read and approved the final manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Fang Liu, MD, Associate Chief Physician, Department of Radiotherapy, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China.
Received: February 2, 2021
Peer-review started: February 2, 2021
First decision: March 6, 2021
Revised: March 18, 2021
Accepted: April 13, 2021
Article in press: April 13, 2021
Published online: May 21, 2021
Core Tip

Core Tip: This retrospective study investigated the changes in serum vitamins before and after chemotherapy for esophageal cancer. Vitamin deficiencies are common in esophageal cancer patients during chemotherapy and may be associated with the change in body mass index. There were correlations between the changes in vitamin A and C concentrations and the change in body mass index during chemotherapy. Vitamin A level after chemotherapy showed a significant difference between males and females, and the vitamin D level after chemotherapy showed a significant difference among different stages. Vitamin supplementation may reduce the adverse effects of chemotherapy and improve the nutritional status.