Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 14, 2019; 25(34): 5017-5025
Published online Sep 14, 2019. doi: 10.3748/wjg.v25.i34.5017
Published online Sep 14, 2019. doi: 10.3748/wjg.v25.i34.5017
Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges
Jeremy Meyer, Surennaidoo Naiken, Niki Christou, Emilie Liot, Christian Toso, Nicolas Christian Buchs, Frédéric Ris, Division of Digestive Surgery, University Hospitals of Geneva, Genève 1211, Switzerland
Author contributions: Meyer J conceived the review and wrote the draft of the manuscript; Meyer J, Naiken S, Christou N, Liot E, Toso C, Buchs NC and Ris F reviewed and accepted the manuscript.
Conflict-of-interest statement: The authors have no conflict of interest to declare.
Open-Access: This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jeremy Meyer, MD, PhD, Surgeon, Division of Digestive Surgery, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Genève 1211, Switzerland. jeremy.meyer@hcuge.ch
Telephone: +41-79-5533182 Fax: +41-22-3727707
Received: March 19, 2019
Peer-review started: March 19, 2019
First decision: August 3, 2019
Revised: August 9, 2019
Accepted: August 19, 2019
Article in press: August 19, 2019
Published online: September 14, 2019
Peer-review started: March 19, 2019
First decision: August 3, 2019
Revised: August 9, 2019
Accepted: August 19, 2019
Article in press: August 19, 2019
Published online: September 14, 2019
Core Tip
Core tip: The present manuscript reviews the current evidence regarding the prevention of anastomotic leak in colorectal surgery. Oral antibiotics and fluorescence angiography might help reduce the incidence of anastomotic leak. Study of the microbiome might offer interesting paths for research. Progress made in anastomotic leak comprehension and prevention might allow reducing the rate of diverting stoma and conduct to a revision of its indications.