Opinion Review
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2019; 25(19): 2271-2278
Published online May 21, 2019. doi: 10.3748/wjg.v25.i19.2271
Cyst fluid glucose: An alternative to carcinoembryonic antigen for pancreatic mucinous cysts
César Vivian Lopes
César Vivian Lopes, Department of Gastroenterology and Digestive Endoscopy, Santa Casa Hospital, Porto Alegre 91410-000, Brazil
Author contributions: Lopes CV defined the concept of the study, evaluated the literature, wrote the manuscript, and provided the figures and tables.
Conflict-of-interest statement: Author does not have any conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: César Vivian Lopes, MD, PhD, Doctor, Department of Gastroenterology and Digestive Endoscopy, Santa Casa Hospital, Rua Prof. Cristiano Fischer 668/1001, Porto Alegre 91410-000, Brazil. drcvlopes@gmail.com
Telephone: +55-51-999628623 Fax: +55-51-999628623
Received: January 7, 2019
Peer-review started: January 7, 2019
First decision: March 14, 2019
Revised: March 30, 2019
Accepted: April 19, 2019
Article in press: April 19, 2019
Published online: May 21, 2019
Core Tip

Core tip: Incidental pancreatic cysts have been found in far more patients with the improvement of cross-sectional imaging tests. Many of these lesions have malignant potential, especially the mucinous lesions, and imaging alone is not enough to guarantee definitive diagnosis. Cyst fluid carcinoembryonic antigen (CEA) has been used as the most important cyst fluid marker to distinguish mucinous from nonmucinous cysts. More recently, glucose has emerged as a useful cyst fluid marker for the identification of pancreatic mucinous cysts with an accuracy similar to or even better than CEA.