Published online May 21, 2019. doi: 10.3748/wjg.v25.i19.2271
Peer-review started: January 7, 2019
First decision: March 14, 2019
Revised: March 30, 2019
Accepted: April 19, 2019
Article in press: April 19, 2019
Published online: May 21, 2019
Core tip: Incidental pancreatic cysts have been found in far more patients with the improvement of cross-sectional imaging tests. Many of these lesions have malignant potential, especially the mucinous lesions, and imaging alone is not enough to guarantee definitive diagnosis. Cyst fluid carcinoembryonic antigen (CEA) has been used as the most important cyst fluid marker to distinguish mucinous from nonmucinous cysts. More recently, glucose has emerged as a useful cyst fluid marker for the identification of pancreatic mucinous cysts with an accuracy similar to or even better than CEA.