Retrospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2017; 23(28): 5206-5215
Published online Jul 28, 2017. doi: 10.3748/wjg.v23.i28.5206
Sex-influenced association of non-alcoholic fatty liver disease with colorectal adenomatous and hyperplastic polyps
Qin-Fen Chen, Xiao-Dong Zhou, Yang-Jie Sun, Dan-Hong Fang, Qian Zhao, Jun-Hua Huang, Yin Jin, Jian-Sheng Wu
Qin-Fen Chen, Yang-Jie Sun, Qian Zhao, Jun-Hua Huang, Yin Jin, Department of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Xiao-Dong Zhou, Department of Cardiovascular Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Dan-Hong Fang, Jian-Sheng Wu, Medical and Health Care Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Author contributions: Chen QF, Zhou XD, Fang DH, Jin Y and Wu JS designed the study; Chen QF, Zhou XD, Sun YJ, Zhao Q and Huang JH collected the data; Chen QF and Zhou XD did the statistical analyses; Chen QF, Zhou XD, Fang DH, Jin Y and Wu JS reviewed the results, interpreted the data, and wrote the manuscript; all authors have made an intellectual contribution to the manuscript and approved the submission.
Institutional review board statement: This article does not contain any studies with human participants or animals performed by either of the authors. No ethics statement is needed.
Informed consent statement: The requirement for informed consent was waived because we retrospectively accessed de-identified data only.
Conflict-of-interest statement: The authors declare that there is no conflict of interest with the paper presented.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Jian-Sheng Wu, Professor, Medical and Health Care Center, The First Affiliated Hospital of Wenzhou Medical University, Xinyuan District, Wenzhou 325000, Zhejiang Province, China. wzwujs@wzhospital.cn
Telephone: +86-577-55578033 Fax: +86-577-55578033
Received: April 24, 2017
Peer-review started: April 25, 2017
First decision: May 16, 2017
Revised: May 24, 2017
Accepted: July 4, 2017
Article in press: July 4, 2017
Published online: July 28, 2017
Core Tip

Core tip: Non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of colorectal adenoma. The association of NAFLD and hyperplastic polyps remains unclear. We utilized 3686 individuals undergoing health checkups to analyze the relationship between NAFLD and colorectal adenomatous and hyperplastic polyps. NAFLD is associated with colorectal adenomatous and hyperplastic polyps in men but not in women.