Case Control Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 14, 2016; 22(46): 10189-10197
Published online Dec 14, 2016. doi: 10.3748/wjg.v22.i46.10189
Use of a saline-coupled bipolar sealer open liver resection for hepatic malignancy: Medical resource use and costs
Christine I Nichols, Joshua G Vose
Christine I Nichols, Joshua G Vose, Medtronic Advanced Energy, 180 International Drive, Portsmouth, NH 03801, United States
Author contributions: Nichols CI and Vose JG designed the research; Nichols CI performed data analyses; Nichols CI and Vose JG analyzed the data; and Nichols CI and Vose JG wrote the paper and revisions.
Institutional review board statement: Given this study used de-identified patient data, it was not subject to Institutional Review Board approval. The study dataset and full study tables are available from the corresponding author.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Joshua G Vose, MD, Medical Director, Medtronic Advanced Energy, 180 International Drive, Portsmouth, NH 03801, United States. joshua.vose@medtronic.com
Telephone: +1-603-8424623 Fax: +1-603-7421488
Received: August 5, 2016
Peer-review started: August 6, 2016
First decision: September 21, 2016
Revised: October 11, 2016
Accepted: November 15, 2016
Article in press: November 16, 2016
Published online: December 14, 2016
Core Tip

Core tip: This study evaluated outcomes associated with use of a saline coupled bipolar sealer during open partial liver resection. Using US Premier insurance claims data, Cases with use of the saline-coupled bipolar sealer (SCBS) were propensity-score matched to controls with no use. A deviation-based cost modeling (DBCM) approach provided an estimate of cost-effectiveness. Results demonstrated that use of the SCBS in open partial liver resection for hepatic malignancy is associated with reduction in the need for transfusion, and is cost-effective in a DBCM analysis. This technology provides an alternative solution for bleeding control in partial liver resection compared to traditional methods.