Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 28, 2016; 22(40): 8940-8948
Published online Oct 28, 2016. doi: 10.3748/wjg.v22.i40.8940
Ansa pancreatica as a predisposing factor for recurrent acute pancreatitis
Takana Yamakawa Hayashi, Wataru Gonoi, Takeharu Yoshikawa, Naoto Hayashi, Kuni Ohtomo
Takana Yamakawa Hayashi, Wataru Gonoi, Kuni Ohtomo, Department of Radiology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan
Takeharu Yoshikawa, Naoto Hayashi, Department of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan
Author contributions: Hayashi YT and Gonoi W designed the research, analyzed data, and drafted the manuscript; Yoshikawa T, Hayashi N and Ohtomo K revised the manuscript; all authors have read and approved the final version to be published.
Supported by JSPS KAKENHI, No. 25870148.
Institutional review board statement: Based on the Declaration of Helsinki, the Research Ethics Committee of the University of Tokyo Hospital approved the prospective and retrospective use of the clinical, biochemical, and radiographic data for the present cross-sectional study.
Informed consent statement: Our institutional review board approved waiver of informed consent for the present cross-sectional study about the patient (pancreatitis) group. All of the subjects of community group provided written informed consent for the comprehensive epidemiological study.
Conflict-of-interest statement: None.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Wataru Gonoi, MD, PhD, Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-8655, Japan.
Telephone: +81-358-008666 Fax: +81-358-008935
Received: June 14, 2016
Peer-review started: June 17, 2016
First decision: July 12, 2016
Revised: August 11, 2016
Accepted: September 14, 2016
Article in press: September 14, 2016
Published online: October 28, 2016
Processing time: 133 Days and 20.7 Hours
Core Tip

Core tip: Ansa pancreatica is a rare anatomical variation of the accessory pancreatic duct and was hypothesized to be a predisposing factor for pancreatitis. However its in vivo prevalence was unknown and no case-control study has confirmed its clinical significance. This study is the first case-control study to determine the non-biased prevalence and provide robust evidence that the presence of ansa pancreatica is significantly associated with recurrent acute pancreatitis, using non-invasive magnetic resonance imaging.