Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.89
Peer-review started: June 3, 2015
First decision: July 14, 2015
Revised: August 8, 2015
Accepted: October 13, 2015
Article in press: October 13, 2015
Published online: January 7, 2016
Core tip: Liver cirrhosis is one of the leading cause of morbidity and mortality in the United States, Europe and Asia. Advanced stages of liver cirrhosis are accompanied by hemodynamic changes of the hepatic vascular system. Four-dimensional (4D) flow magnetic resonance imaging (MRI) has been validated for the clinical assessment of the liver blood flow in patients with advanced liver cirrhosis. It represents a method that supplements Doppler ultrasound and provides important additional information on the vessel system in difficult patients. The purpose of this review is to provide insights into 4D flow MRI for blood flow visualization and quantification in patients with advanced liver cirrhosis.