Controversies regarding and perspectives on clinical utility of biomarkers in hepatocellular carcinoma
Pei-Pei Song, Ju-Feng Xia, Yoshinori Inagaki, Kiyoshi Hasegawa, Yoshihiro Sakamoto, Norihiro Kokudo, Wei Tang, Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, the University of Tokyo, Tokyo 113-8655, Japan
Author contributions: Kokudo N and Tang W designed the research; Song PP, Xia JF and Inagaki Y conducted the data collection and analysis; Song PP wrote the initial draft of the paper; Hasegawa K and Sakamoto Y revised the paper; all authors were involved in the interpretation of the data and writing the paper; all authors approved the final version of the manuscript and take responsibility for its content.
Supported by Grants-in-Aid from the Ministry of Education, Science, Sports, and Culture of Japan.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Wei Tang, MD, PhD, Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, the University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan. email@example.com
Telephone: +81-3-58009269 Fax: +81-3-56843989
Received: May 15, 2015
Peer-review started: May 19, 2015
First decision: July 14, 2015
Revised: July 27, 2015
Accepted: October 13, 2015
Article in press: October 13, 2015
Published online: January 7, 2016