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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 14, 2015; 21(6): 1821-1826
Published online Feb 14, 2015. doi: 10.3748/wjg.v21.i6.1821
Published online Feb 14, 2015. doi: 10.3748/wjg.v21.i6.1821
New parameter in diagnosis of acute appendicitis: Platelet distribution width
Bulent Dinc, Department of General Surgery, Ataturk State Hospital, Antalya 07040, Turkey
Alten Oskay, Department of Emergency, Denizli State Hospital, Denizli 20010, Turkey
Selcan Enver Dinc, Department of Emergency, Isparta State Hospital, Isparta 32100, Turkey
Bilge Bas, Department of Gastroenterology, Ataturk State Hospital, Antalya 07040, Turkey
Sabri Tekin, Department of Surgery, Medical Park Hospitals, Antalya 07160, Turkey
Author contributions: Dinc B and Oskay A planned the study; Dinc B, Oskay A, Dinc SE, and Tekin S collected the data; Dinc B performed the data analysis; Dinc B and Bas B interpreted the data; Dinc B and Dinc SE wrote the paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Bulent Dinc, MD, Department of General Surgery, Ataturk State Hospital, Gulluk Street, Antalya 07040, Turkey. bulent1999@yahoo.com
Telephone: +90-242-3454550 Fax: +90-242-3343373
Received: July 10, 2014
Peer-review started: July 10, 2014
First decision: August 15, 2014
Revised: August 24, 2014
Accepted: October 14, 2014
Article in press: October 15, 2014
Published online: February 14, 2015
Peer-review started: July 10, 2014
First decision: August 15, 2014
Revised: August 24, 2014
Accepted: October 14, 2014
Article in press: October 15, 2014
Published online: February 14, 2015
Core Tip
Core tip: The diagnosis of acute appendicitis can be difficult and confusing. A rapid and accurate diagnosis is important because of potential complications, therefore, new biomarkers for diagnosis are needed. This study investigated the diagnostic accuracy of indicators of platelet activation, namely mean platelet volume and platelet distribution width, in acute appendicitis patients. Results shows that platelet distribution width analysis can be used for diagnosis of acute appendicitis without requiring additional tests. Therefore, it reduces the cost and loss of time.