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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 14, 2015; 21(46): 13195-13200
Published online Dec 14, 2015. doi: 10.3748/wjg.v21.i46.13195
Published online Dec 14, 2015. doi: 10.3748/wjg.v21.i46.13195
Recurrent gastric neuroendocrine tumors treated with total gastrectomy
Myounghwa Jung, Jung-Wook Kim, Jae-Young Jang, Sun Hee Park, Young Woon Chang, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul 130-702, South Korea
Yong Ho Kim, Department of Surgery, College of Medicine, Kyung Hee University, Seoul 130-702, South Korea
Youn Wha Kim, Department of Pathology, College of Medicine, Kyung Hee University, Seoul 130-702, South Korea
Author contributions: Jung M and Kim JW contributed equally to this work; Kim JW, Chang YW, Kim YH, Jang JY, Kim YW and Park SH designed research; Jung M wrote the paper; and Jang JY approved the final version.
Conflict-of-interest statement: All authors declare no conflicts of interest
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jae-Young Jang, MD, PhD, Department of Internal Medicine, College of Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemoongu, Seoul 130-702, South Korea. jyjang@khu.ac.kr
Telephone: +82-2-9588200 Fax: +82-2-9681848
Received: February 6, 2015
Peer-review started: February 9, 2015
First decision: April 24, 2015
Revised: June 2, 2015
Accepted: August 28, 2015
Article in press: August 31, 2015
Published online: December 14, 2015
Peer-review started: February 9, 2015
First decision: April 24, 2015
Revised: June 2, 2015
Accepted: August 28, 2015
Article in press: August 31, 2015
Published online: December 14, 2015
Core Tip
Core tip: This rare case exhibited the full hyperplasia-dysplasia-neoplasia sequence of enterochromaffin-like cells in a single specimen. This case clarifies the pathogenesis of gastric neuroendocrine tumors. Furthermore, this case revealed that total gastrectomy is a treatment option for patients with recurrent neuroendocrine tumors following excision.