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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 28, 2015; 21(44): 12660-12666
Published online Nov 28, 2015. doi: 10.3748/wjg.v21.i44.12660
Published online Nov 28, 2015. doi: 10.3748/wjg.v21.i44.12660
Capsule enteroscopy is useful for the therapeutic management of Crohn’s disease
João Santos-Antunes, Hélder Cardoso, Susana Lopes, Margarida Marques, Amadeu CR Nunes, Guilherme Macedo, Gastroenterology Department, Faculty of Medicine, Hospital de São João, 4200-319 Porto, Portugal
João Santos-Antunes, Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
Author contributions: Santos-Antunes J wrote the paper, collected the data, elaborated the database, analyzed the statistics, and contributed to the interpretation and literature review; Cardoso H contributed to capsule reading, data collection, and study design; Lopes S contributed to patient follow-up and scientific collaboration; Marques M contributed to capsule reading and scientific collaboration; Nunes ACR contributed to patient follow-up and scientific collaboration; Macedo G contributed to study design, paper writing, and scientific revision of the manuscript.
Institutional review board statement: Due to its retrospective nature, no ethical concerns were raised for the writing of this manuscript.
Informed consent statement: Informed consent for CE and Patency capsule procedures was obtained for every patient. Due to its retrospective nature, no informed consent for the writing of this manuscript was applicable.
Conflict-of-interest statement: The authors state that they have no conflicts of interest to declare.
Data sharing statement: No additional data available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: João Santos-Antunes, MD, Department of Gastroenterology, Faculty of Medicine, Centro Hospitalar S. João. Alameda Prof. Hernani Monteiro, 4200-319 Porto, Portugal. joao.claudio.antunes@gmail.com
Telephone: +351-22-5513600 Fax: +351-22-5513601
Received: April 24, 2015
Peer-review started: April 26, 2015
First decision: June 2, 2015
Revised: June 30, 2015
Accepted: August 30, 2015
Article in press: August 31, 2015
Published online: November 28, 2015
Peer-review started: April 26, 2015
First decision: June 2, 2015
Revised: June 30, 2015
Accepted: August 30, 2015
Article in press: August 31, 2015
Published online: November 28, 2015
Core Tip
Core tip: Our work analyzed the therapeutic management of patients with Crohn’s disease (CD) and concluded that a very significant proportion of patients modify their therapeutic regimens after performing video capsule endoscopy (VCE), even in those with long-term disease or those without symptoms. This finding highlights the importance of this procedure in the management of CD. The systematic use of Patency capsule is controversial; however, we showed in our study that after excluding patients with negative patency, who did not undergo VCE, none of the patients had video capsule retention during VCE, highlighting the importance of Patency capsule in this setting.