Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 21, 2015; 21(43): 12498-12504
Published online Nov 21, 2015. doi: 10.3748/wjg.v21.i43.12498
Intraductal papillary neoplasm of the bile ducts: A case report and literature review
Yaohong Tan, Clara Milikowski, Yanelba Toribio, Adam Singer, Claudia P Rojas, Monica T Garcia-Buitrago
Yaohong Tan, Clara Milikowski, Yanelba Toribio, Claudia P Rojas, Monica T Garcia-Buitrago, Department of Pathology, Jackson Memorial Hospital, University of Miami Miller School of Medicine, Miami, FL 33136, United States
Adam Singer, Department of Radiology, Jackson Memorial Hospital, University of Miami Miller School of Medicine, Miami, FL 33136, United States
Author contributions: Tan Y contributed to writing and revising the manuscript; Milikowski C, Toribio Y and Rojas CP contributed to editing this manuscript; Singer A contributed to the radiology; and Garcia-Buitrago MT contributed to concept, design and editing of this manuscript.
Conflict-of-interest statement: The authors declare no potential conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Monica T Garcia-Buitrago, MD, Department of Pathology, Jackson Memorial Hospital, University of Miami Miller School of Medicine,1611 NW 12th Avenue, Holtz Center, Room 2042 E, Miami, FL 33136, United States. mgarcia22@med.miami.edu
Telephone: +1-305-5856520 Fax: +1-305-5856526
Received: May 7, 2015
Peer-review started: May 11, 2015
First decision: June 2, 2015
Revised: June 20, 2015
Accepted: August 25, 2015
Article in press: August 25, 2015
Published online: November 21, 2015
Core Tip

Core tip: Intraductal papillary neoplasm of the bile duct (IPNB) is very rare in the United States. In this article, we reported the first IPNB patient we encountered. The patient is a 38-year-old female who is one of the youngest patients that have been reported. She was found to have intraductal papillary masses in the common hepatic duct and liver parenchyma. The diagnosis was IPNB, gastric subtype. In a search of PubMed database, we collected 354 IPNB patients from 22 articles and summarized the clinico-pathologic features including geographic distribution, age, gender, symptoms, location, microscopic subtypes, differential diagnosis, pathogenesis and therapeutic options.