Case Control Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2015; 21(27): 8358-8365
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8358
Clinical features of second primary cancers arising in early gastric cancer patients after endoscopic resection
Jung-Wook Kim, Jae-Young Jang, Young Woon Chang, Yong Ho Kim
Jung-Wook Kim, Jae-Young Jang, Young Woon Chang, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul 130-702, South Korea
Yong Ho Kim, Department of Surgery, College of Medicine, Kyung Hee University, Seoul 130-702, South Korea
Author contributions: Kim JW and Jang JY designed the study; Chang YW and Kim YH analyzed data; Kim JW wrote the manuscript; Chang YW revised the paper; and Jang JY approved the final version.
Supported by Kyung Hee University for the young medical researcher in 2007 (KHU-20071510).
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Kyung Hee University Hospital (KMC IRB 1217-03)
Informed consent statement: Because this was a retrospective study with minimal risk to patients, it was exempted from obtaining informed consent by the IRB.
Conflict-of-interest statement: All authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jae-Young Jang, MD, PhD, Department of Internal Medicine, College of Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemoongu, Seoul 130-702, South Korea. jyjang@khu.ac.kr
Telephone: +82-2-9588200 Fax: +82-2-9681848
Received: February 24, 2015
Peer-review started: February 26, 2015
First decision: March 26, 2015
Revised: April 7, 2015
Accepted: May 21, 2015
Article in press: May 21, 2015
Published online: July 21, 2015
Core Tip

Core tip: In this study, we investigate the incidence and distribution of second primary cancers (SPCs) in early gastric cancer (EGC) patients who underwent endoscopic resection (ER) compared to advanced gastric cancer patients who underwent surgery. Although SPCs developed rather commonly in gastric cancer patients, no significant risk factors were identified for their development. Therefore, endoscopists should perform close surveillance and establish follow-up programs for SPC detection after use of ER to treat EGC.