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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 14, 2015; 21(18): 5739-5743
Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5739
Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5739
Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor
Sung Bum Kim, Si Hyung Lee, Department of Internal Medicine, Yeungnam University Hospital, Daegu 705-802, South Korea
Mi Jin Gu, Department of Pathology, Yeungnam University Hospital, Daegu 705-802, South Korea
Author contributions: Lee SH supervised, proof-read, and made required corrections; all authors contributed to designing the report, as well as to the editing and writing of the manuscript.
Ethics approval: This study was reviewed and approved by the institutional review board of Yeungnam University Hospital.
Informed consent: The patient signed informed consent.
Conflict-of-interest: No potential conflict of interest relevant to this article was reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Si Hyung Lee, MD, Department of Internal Medicine, Yeungnam University Hospital, 170 Hyeonchung-ro, Nam-gu, Daegu 705-802, South Korea. dr9696@nate.com
Telephone: +82-53-6203830 Fax: +82-53-6548386
Received: November 18, 2014
Peer-review started: November 19, 2014
First decision: January 8, 2015
Revised: January 28, 2015
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: May 14, 2015
Peer-review started: November 19, 2014
First decision: January 8, 2015
Revised: January 28, 2015
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: May 14, 2015
Core Tip
Core tip: This is the first reported case of malignant gastrointestinal neuroectodermal tumor arising in the esophagus. Malignant gastrointestinal neuroectodermal tumor is a tumor with a similar morphology, immunophenotype, and molecular genetic features to clear cell sarcoma of tendons and aponeurosis lacking melanocytic differentiation arising in the gastrointestinal tract. Malignant gastrointestinal neuroectodermal tumors show aggressive disease behavior with a poor prognosis.