Prospective Study
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World J Gastroenterol. Nov 21, 2014; 20(43): 16306-16310
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16306
Magnifying narrow-band imaging with acetic acid to diagnose early colorectal cancer
Norihiro Goto, Toshihiro Kusaka, Yumi Tomita, Hideyuki Tanaka, Yoshio Itokawa, Yorimitsu Koshikawa, Daisuke Yamaguchi, Yoshitaka Nakai, Shigehiko Fujii, Hiroyuki Kokuryu
Norihiro Goto, Toshihiro Kusaka, Yumi Tomita, Hideyuki Tanaka, Yoshio Itokawa, Yorimitsu Koshikawa, Daisuke Yamaguchi, Yoshitaka Nakai, Shigehiko Fujii, Hiroyuki Kokuryu, Department of Gastroenterology and Hepatology, Kyoto Katsura Hospital, Kyoto 615-8256, Japan
Author contributions: Goto N, Kusaka T, Fujii S and Kokuryu H designed the study; Goto N, Kusaka T, Tomita Y, Tanaka H, Itokawa Y, Koshikawa Y, Yamaguchi D, Nakai Y and Fujii S performed the colonoscopy; Goto N analyzed the data and wrote the manuscript.
Correspondence to: Norihiro Goto, MD, Department of Gastroenterology and Hepatology, Kyoto Katsura Hospital, 17 Yamada Hiraocho, Nishikyoku, Kyoto 615-8256, Japan. norihirogoto@hotmail.co.jp
Telephone: +81-75-3915811 Fax: +81-75-3923517
Received: March 17, 2014
Revised: June 8, 2014
Accepted: July 11, 2014
Published online: November 21, 2014
Core Tip

Core tip: Differentiating early colorectal adenocarcinomas from adenomas using magnifying endoscopy with narrow-band imaging can sometimes be difficult because the surface pattern is frequently obscure. Magnifying endoscopy with acetic acid spray and narrow-band imaging (MA-NBI) accentuates the surface pattern of colorectal polyps. This study showed that MA-NBI and magnifying endoscopy with crystal violet staining (M-CV) are useful for differentiating early colorectal adenocarcinomas from adenomas. Moreover, MA-NBI is more time- and cost-effective than M-CV and could be beneficial for routine colonoscopies in terms of diagnostic accuracy, efficiency, and cost-effectiveness.