Case Report
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World J Gastroenterol. Nov 7, 2014; 20(41): 15448-15453
Published online Nov 7, 2014. doi: 10.3748/wjg.v20.i41.15448
Benign giant-cell tumor of the common bile duct: A case report
Dan-Dan Wang, Ya-Min Zheng, Liang-Hong Teng, Yan-Ni Sun, Wei Gao, Lei-Ming Wang, Yue-Hua Wang, Fei Li, De-Hong Lu
Dan-Dan Wang, Liang-Hong Teng, Yan-Ni Sun, Wei Gao, Lei-Ming Wang, De-Hong Lu, Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
Ya-Min Zheng, Yue-Hua Wang, Fei Li, Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
Author contributions: Wang DD and Zheng YM contributed equally to this study; Sun YN and Lu DH designed the study; Teng LH, Wang YH and Li F collected the patient’s clinical data; Gao W and Wang LM performed the experiments; Wang DD and Zheng YM analyzed the data and wrote the manuscript.
Correspondence to: Dr. De-Hong Lu, Department of Pathology, Xuanwu Hospital, Capital Medical University, No. 45, Changchun Street, Xicheng District, Beijing 100053, China. ludehong05@sina.com
Telephone: +86-10-83198610 Fax: +86-10-63042809
Received: March 5, 2014
Revised: May 7, 2014
Accepted: August 13, 2014
Published online: November 7, 2014
Core Tip

Core tip: In visceral organs, different types of carcinomas, such as anaplastic spindle- and giant-cell carcinomas of the gallbladder and extrahepatic bile duct, may contain a variable number of osteoclast-like giant cells. It is crucial to separate those carcinomas with osteoclast-like giant cells from giant-cell tumors because of their striking differences in prognosis. This case report represents the fifth case of a primary giant-cell tumor of the common bile duct in the English-language literature. We also review several reported cases to summarize clinical information about this rare tumor.