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World J Gastroenterol. Aug 28, 2014; 20(32): 11230-11240
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11230
Strategies for early detection of resectable pancreatic cancer
Keiichi Okano, Yasuyuki Suzuki
Keiichi Okano, Yasuyuki Suzuki, Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan
Author contributions: Okano K drafted this manuscript, which was revised by Suzuki K.
Correspondence to: Keiichi Okano, MD, PhD, Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University, 1750-1, Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan. kokano@kms.ac.jp
Telephone: +81-87-8912438 Fax: +81-87-8912439
Received: November 1, 2013
Revised: March 4, 2014
Accepted: April 15, 2014
Published online: August 28, 2014
Core Tip

Core tip: To improve the prognosis of patients with pancreatic cancer, it is essential to detect tumors at early stages, when they are resectable. The cancer of the pancreas screening program has reached several conclusions and recommendations for the management of patients who are at an increased risk of familial pancreatic cancer. Furthermore, genetic, epigenetic, and proteomics research have improved the understanding of the mechanisms of this disease, potentially offering biomarkers that could allow the cancer to be detected early. This article reviews strategies for the early detection of resectable pancreatic cancer.