Meta-Analysis
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World J Gastroenterol. Aug 7, 2014; 20(29): 10174-10182
Published online Aug 7, 2014. doi: 10.3748/wjg.v20.i29.10174
Clinical outcome of small hepatocellular carcinoma after different treatments: A meta-analysis
Wei Dong, Ting Zhang, Zhen-Guang Wang, Hui Liu
Wei Dong, Ting Zhang, Zhen-Guang Wang, Hui Liu, the Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China
Author contributions: Liu H designed the research and provided financial support for this study; Dong W and Zhang T performed the literature search; Wang ZG collected the clinical data from the literature and analyzed these data; Dong W wrote the manuscript.
Supported by National Key Basic Research Program of China - 973 Program, No. 2012CB526706; International Science and Technology Cooperation Program of the Ministry of Science and Technology, No. 2011DFA32980; The Innovation Program of Shanghai Municipal Education Commission, No. 2013ZZ060; and the National Natural Science Foundation of China, No. NSFC81271694
Correspondence to: Hui Liu, Associate Professor, the Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, NO.225, Changhai Road, Yangpu district, Shanghai 200438, China. happyehbh@163.com
Telephone: +86-21-65389998 Fax: +86-21-65562400
Received: January 4, 2014
Revised: February 26, 2014
Accepted: March 19, 2014
Published online: August 7, 2014
Core Tip

Core tip: The efficacy of surgical resection over nonsurgical ablation for the treatment of small hepatocellular carcinoma has long been debated. In previous studies, a meta-analysis was conducted on cases of resection (RES) vs radiofrequency ablation or RES vs other single nonsurgical ablation methods. Our meta-analysis was designed to determine the superior choice of treatment for small hepatocellular carcinoma from among surgical resection and nonsurgical ablation methods.