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World J Gastroenterol. Jun 7, 2014; 20(21): 6420-6424
Published online Jun 7, 2014. doi: 10.3748/wjg.v20.i21.6420
Published online Jun 7, 2014. doi: 10.3748/wjg.v20.i21.6420
Simple animal model of Helicobacter pylori infection
Duangporn Werawatganon, Department of Physiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand
Author contributions: Werawatganon D solely contributed to this paper.
Correspondence to: Duangporn Werawatganon, MD, Associate Professor, Department of Physiology, Faculty of Medicine, Chulalongkorn University, 254 Phayathai Road, Pathumwan, Bangkok 10330, Thailand. dr.duangporn@gmail.com
Telephone: +66-2-2564267 Fax: +66-2-2564267-2823
Received: October 10, 2013
Revised: March 9, 2014
Accepted: March 19, 2014
Published online: June 7, 2014
Revised: March 9, 2014
Accepted: March 19, 2014
Published online: June 7, 2014
Core Tip
Core tip:Helicobacter pylori (H. pylori) causes significant gastroduodenal diseases. Experimental animal models play an important role in helping us understand the pathogenesis and discovering new therapeutic strategies. Previous H. pylori-associated gastritis candidate animal models have included gnotobiotic piglets, non-human primates, pigs, dogs, cats, gerbils, and mice. Rat models of H. pylori infection use a difficult technique and take a long time to establish. In this study, we developed a simple model of H. pylori infection in rats for further research.