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World J Gastroenterol. Apr 14, 2014; 20(14): 4093-4101
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.4093
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.4093
Effect of precut sphincterotomy on post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis
Abhishek Choudhary, Jessica Winn, Sameer Siddique, Murtaza Arif, Zainab Arif, Ghassan M Hammoud, Jamal A Ibdah, Matthew L Bechtold, Division of Gastroenterology, Department of Internal Medicine, University of Missouri-Columbia, M580 Health Sciences Center, Columbia, MO 65212, United States
Srinivas R Puli, Division of Gastroenterology and Hepatology, University of Illinois, Peoria Campus, OSF Saint Francis Medical Center, Peoria, IL 61637, United States
Author contributions: Choudhary A, Winn J and Bechtold ML designed research; Choudhary A, Winn J, Arif Z, Siddique S and Arif M performed research; Puli SR, Hammoud GM and Ibdah JA contributed with analytic tools; Choudhary A, Bechtold ML and Puli SR analyzed data; Choudhary A, Arif M and Bechtold ML wrote the paper.
Correspondence to: Abhishek Choudhary, MD, Assistant Professor, Division of Gastroenterology, Department of Internal Medicine, University of Missouri-Columbia, M580 Health Sciences Center, DC043.00, Five Hospital Drive, Columbia, MO 65212, United States. choudharya@health.missouri.edu
Telephone: +1-573-8827349 Fax: +1-573-8844595
Received: October 18, 2013
Revised: December 27, 2013
Accepted: January 14, 2014
Published online: April 14, 2014
Revised: December 27, 2013
Accepted: January 14, 2014
Published online: April 14, 2014
Core Tip
Core tip: Multiple trials are available in literature, but still the optimal timing of precut sphincterotomy is debatable. We conducted systemic review and meta-analysis to explore the effect of early precut sphincterotomy on post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis with emphasis on analysis of optimal timing of precut sphincterotomy. Our meta-analysis showed that early precut sphincterotomy decreases the odds of post-ERCP pancreatitis, particularly if done within 5-10 min of failed cannulation without compromising cannulation rates or increasing other complications.