Published online Jun 28, 2013. doi: 10.3748/wjg.v19.i24.3831
Revised: February 10, 2013
Accepted: April 28, 2013
Published online: June 28, 2013
Core tip: Progressive population aging worldwide demands consensus development for decision making to treat elderly patients. A simple comparison of survival days is confounded by aging; therefore, age compensation is mandatory to evaluate survival benefits among different age groups. In this study, age difference was compensated by life expectancy in a hepatocellular carcinoma cohort. The authors suggested that age itself might not be a critical determinant for the selection of a therapeutic option. This study emphasizes the importance of clarifying risk determinants specific for elderly patients with respect to individual aspects and medical economy.