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World J Gastroenterol. Apr 14, 2013; 19(14): 2187-2196
Published online Apr 14, 2013. doi: 10.3748/wjg.v19.i14.2187
Published online Apr 14, 2013. doi: 10.3748/wjg.v19.i14.2187
Comparative evaluation of intragastric bile acids and hepatobiliary scintigraphy in the diagnosis of duodenogastric reflux
Teng-Fei Chen, Praveen K Yadav, Rui-Jin Wu, Wei-Hua Yu, Chang-Qin Liu, Hui Lin, Zhan-Ju Liu, Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University, Shanghai 200072, China
Author contributions: Chen TF and Yadav PK contributed equally to this work; Chen TF and Yadav PK collected and analysed data and drafted manuscript; Wu RJ and Lin H contributed to revision of manuscript; Yu WH and Liu CQ contributed to the collection of the data; Liu ZJ contributed by developing study concept and design, interpretation of data, and critical revision of manuscript.
Supported by Grants from the National Natural Science Foundation of China, No. 81061120521 and No. 81270470; Shanghai Science and Technology Commission, No. 12XD1404000
Correspondence to: Dr. Zhan-Ju Liu, Professor, Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University, Shanghai 200072, China. zhanjuliu@yahoo.com
Telephone: +86-21-66301164 Fax: +86-21-66303893
Received: December 20, 2012
Revised: January 25, 2013
Accepted: February 5, 2013
Published online: April 14, 2013
Revised: January 25, 2013
Accepted: February 5, 2013
Published online: April 14, 2013
Core Tip
Core tip: The study results suggest that total bile acid is the most important factor of the bile acids to determine duodenogastric reflux (DGR) by using a variety of statistical methods. Using the receiver operator curve, we found the hepatobiliary scintigraphy is better than the examination of gastric juice in the diagnosis of DGR. From this study, the biggest revelation is that we can research other medical problems particularly using many statistical methods.