Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.103
Peer-review started: May 20, 2015
First decision: June 23, 2015
Revised: July 22, 2015
Accepted: September 30, 2015
Article in press: September 30, 2015
Published online: January 7, 2016
Gadoxetic acid improves detection and characterization of focal liver lesions in cirrhotic patients and can estimate liver function in patients undergoing liver resection. The purpose of this article is to describe the optimal gadoxetic acid study protocol for the liver, the unique characteristics of gadoxetic acid, the differences between gadoxetic acid and extra-cellular gadolium chelates, and the differences in phases of enhancement between cirrhotic and normal liver using gadoxetic acid. We also discuss how to obtain and recognize an adequate hepatobiliary phase.
Core tip: Hepatobiliary contrast materials improve detection and characterization of focal liver lesions in cirrhotic patients and can measure liver function. Familiarity with unique characteristics of gadoxetic acid is crucial to achieve an optimal magnetic resonance examination of the liver. In this review, we discuss the protocol for gadoxetic acid enhanced magnetic resonance imaging of the liver and describe differences between gadoxetic acid and extra-cellular contrast materials.