Clinical Articles
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 25, 1996; 2(2): 79-81
Published online Jun 25, 1996. doi: 10.3748/wjg.v2.i2.79
Histopathological study of hepatocellular carcinoma after transcatheter hepatic arterial embolization
Xiao-Long Ji, Yong-Xiong Liu, Yue-Hua Wang, Hong Zhao
Xiao-Long Ji, Department of Pathology, Chinese PLA General Hospital, Beijing 100853, China
Yong-Xiong Liu, Yue-Hua Wang, Department of Surgery, Chinese PLA General Hospital, Beijing 100853, China
Hong Zhao, Department of Radiology, Chinese PLA General Hospital, Beijing 100853, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Xiao-Long Ji, Professor, Department of Pathology, Chinese PLA General Hospital, Beijing 100853, China
Received: January 15, 1996
Revised: March 20, 1996
Accepted: May 10, 1996
Published online: June 25, 1996
Abstract

AIM: To study the histopathological changes in hepatocellular carcinoma (HCC) after transcatheter arterial embolization (TAE).

METHODS: Histopathological analysis was made in 39 cases of liver neoplasms after TAE and 11 cases of liver neoplasms after digital selective angiography (DSA); data assessed included pathological type, histological grade, necrotic degree, encapsulation, times of treatment, vasculature injury and lymphocyte infiltration.

RESULTS: Following DSA, histological analysis identified 6 cases with 100% necrosis, 14 cases with 30%-95% necrosis, 19 cases with 0%-5% necrosis after TAE and 11 cases without necrosis. The presence of necrosis was related to the pathological type, encapsulation and vasculature injury, but not to the histological grade, times of treatment or lymphocyte infiltration of the liver neoplasms.

CONCLUSION: TAE is an effective therapy for late-stage HCC. Encapsulated HCC is a preferable indicator for TAE.

Keywords: Carcinoma, hepatocellular/therapy; Carcinoma, hepatocellular/pathology; Embolization, therapeutic; Liver neoplasms/therapy; Liver neoplasms/pathology