Published online Jun 25, 1996. doi: 10.3748/wjg.v2.i2.79
Revised: March 20, 1996
Accepted: May 10, 1996
Published online: June 25, 1996
AIM: To study the histopathological changes in hepatocellular carcinoma (HCC) after transcatheter arterial embolization (TAE).
METHODS: Histopathological analysis was made in 39 cases of liver neoplasms after TAE and 11 cases of liver neoplasms after digital selective angiography (DSA); data assessed included pathological type, histological grade, necrotic degree, encapsulation, times of treatment, vasculature injury and lymphocyte infiltration.
RESULTS: Following DSA, histological analysis identified 6 cases with 100% necrosis, 14 cases with 30%-95% necrosis, 19 cases with 0%-5% necrosis after TAE and 11 cases without necrosis. The presence of necrosis was related to the pathological type, encapsulation and vasculature injury, but not to the histological grade, times of treatment or lymphocyte infiltration of the liver neoplasms.
CONCLUSION: TAE is an effective therapy for late-stage HCC. Encapsulated HCC is a preferable indicator for TAE.