Case Report
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World J Gastroenterol. Mar 21, 2013; 19(11): 1845-1849
Published online Mar 21, 2013. doi: 10.3748/wjg.v19.i11.1845
Muco-submucosal elongated polyps of the gastrointestinal tract: A case series and a review of the literature
Char Loo Tan, Sze Hwa Tan, Jimmy BY So, Fredrik Petersson
Char Loo Tan, Sze Hwa Tan, Fredrik Petersson, Department of Pathology, National University Hospital System, Singapore 119074, Singapore
Jimmy BY So, Department of Surgery, National University Hospital System, Singapore 119074, Singapore
Author contributions: Tan CL, Tan SH, So JBY, Petersson F contributed to the manuscript writing and revision.
Correspondence to: Fredrik Petersson, MD, PhD, Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. fredrikpetersson@live.se
Telephone: +65-97-714890 Fax: +65-67-780671
Received: September 7, 2012
Revised: January 8, 2013
Accepted: January 23, 2013
Published online: March 21, 2013
Processing time: 195 Days and 23.2 Hours
Abstract

We present three cases of gastrointestinal muco-submucosal elongated polyps, two located in the duodenum and one in the descending colon. All three cases had a characteristic, “worm-like” endoscopic appearance and were lined by unremarkable mucosa. The vascular component was located in the submucosa and was composed of a mixture of variably dilated blood vessels (capillaries and veins) and lymphatics. The duodenal polyps displayed lipomatous metaplasia of the submucosal stroma. The dual vascular phenotype of the vascular component was confirmed by immunohistochemistry with D2-40 and CD31.

Keywords: Muco-submucosal elongated polyp; Vascular malformation; Endoscopic ultrasonography; Angioma; Endoscopy