Case Report
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World J Gastroenterol. Dec 21, 2012; 18(47): 7118-7121
Published online Dec 21, 2012. doi: 10.3748/wjg.v18.i47.7118
Esophageal granular cell tumors: Report of 9 cases and a literature review
Guo-Qiang Xu, Hong-Tan Chen, Cheng-Fu Xu, Xiao-Dong Teng
Guo-Qiang Xu, Hong-Tan Chen, Cheng-Fu Xu, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Xiao-Dong Teng, Department of Pathology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Xu GQ designed the research; Xu GQ, Chen HT, Xu CF and Teng XD performed the research; Xu GQ analyzed the data; Chen HT and Xu CF wrote the paper.
Correspondence to: Guo-Qiang Xu, MD, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China. zyxgq@sina.cn
Telephone: +86-571-87236518 Fax: +86-571-87236611
Received: July 10, 2012
Revised: October 13, 2012
Accepted: October 30, 2012
Published online: December 21, 2012
Abstract

Esophageal granular cell tumors (GCTs) are rare tumors of the esophagus. We evaluated the clinical and pathologic features of 9 esophageal GCT patients (5 men and 4 women) from our institute and reviewed the related disease literature. Patient age ranged from 25 to 53 years (mean: 41 years). All the patients were asymptomatic or presented with non-specific symptoms. Most GCTs occurred in the distal esophagus and were less than 6 mm in diameter. Computational analysis showed that the average gray-scale endoscopic ultrasound images of esophageal GCTs were greater than that of esophageal leiomyomas. Eight patients were treated by endoscopic resection, and 1 patient underwent surgical excision. No post-therapy recurrence or metastasis developed during follow-up (mean: 36.4 mo, range: 1-72 mo).

Keywords: Esophageal granular cell tumor, Endoscopic ultrasonography, Computer images analysis