Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2022; 28(25): 2994-3000
Published online Jul 7, 2022. doi: 10.3748/wjg.v28.i25.2994
Early gastric cancer presenting as a typical submucosal tumor cured by endoscopic submucosal dissection: A case report
Joon Hyun Cho, Si Hyung Lee
Joon Hyun Cho, Si Hyung Lee, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu 42415, South Korea
Author contributions: Cho JH and Lee SH were responsible for the design of this report, the acquisition of clinical data, and writing and revision of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient regarding the publication of this report and accompanying images.
Conflict-of-interest statement: The authors have no conflict of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Si Hyung Lee, MD, Professor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu 42415, South Korea. dr9696@gmail.com
Received: December 18, 2021
Peer-review started: December 18, 2021
First decision: March 10, 2022
Revised: March 12, 2022
Accepted: May 27, 2022
Article in press: May 27, 2022
Published online: July 7, 2022
Core Tip

Core Tip: We experienced an exceptionally rare case of early gastric cancer presenting as submucosal tumor (SMT) that was successfully treated by endoscopic submucosal dissection (ESD) alone, although the procedure was performed four years after first detection due to patient refusal and follow-up loss. The present case cautions that SMT-like gastric cancer should be included in the differential diagnosis when a hypoechogenic mass is detected in the 2nd or 3rd layer by endoscopic ultrasound, regardless of size and the absence of findings suggesting malignancy. When diagnosis is uncertain, invasive techniques such as diagnostic endoscopic mucosal resection or ESD, which can potentially be used for therapeutic purposes, should be considered and close follow-up is recommended.