Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 14, 2015; 21(2): 563-570
Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.563
Impression of prognosis regarding pathologic stage after preoperative chemoradiotherapy in rectal cancer
Kyungyeon Hwang, In Ja Park, Chang Sik Yu, Seok-Byung Lim, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Jin Cheon Kim
Kyungyeon Hwang, In Ja Park, Chang Sik Yu, Seok-Byung Lim, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Jin Cheon Kim, Department of Colon and Rectal Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul 138-736, South Korea
Author contributions: Park IJ designed study and write manuscript; Hwang K write manuscript; Yu CS, Lim SB, Lee JL, Yoon YS, Kim CW and Kim JC provided clinical data and were also involved in editing the manuscript; Yu CS and Kim JC provided critical comments on manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: In Ja Park, MD, PhD, Assistant Professor, Department of Colon and Rectal Surgery, University of Ulsan College of Medicine and Asan Medical Center, 86 Asanbyeongwon-gil, Songpa-gu, Seoul 138-736, South Korea. ipark@amc.seoul.kr
Telephone: +82-2-30103937 Fax: +82-2-4749027
Received: May 6, 2014
Peer-review started: May 7, 2014
First decision: June 10, 2014
Revised: June 30, 2014
Accepted: August 28, 2014
Article in press: August 28, 2014
Published online: January 14, 2015
Core Tip

Core tip: Strictly speaking, there is no common objective guideline to predict prognosis and give adjuvant treatment according to risk stratification. Patients who show good response were thought to have good prognosis. However, expected value of recurrence-free survival or recurrence rate was not suggested especially in patients who did not show good response to patients receiving preoperative chemoradiotherapy (PCRT). In addition, how to measure the response level was variable. The present study suggests impression of prognosis based on pathologic stage, which is objective, after PCRT and radical resection and show stage-by-stage comparison with those without PCRT to give impression of prognosis by using familiar stage-based prognosis.