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World J Gastroenterol. Nov 7, 2013; 19(41): 7089-7096
Published online Nov 7, 2013. doi: 10.3748/wjg.v19.i41.7089
Published online Nov 7, 2013. doi: 10.3748/wjg.v19.i41.7089
Magnifying endoscopy for the diagnosis of specialized intestinal metaplasia in short-segment Barrett’s esophagus
Nam Seok Ham, Jae Young Jang, Sung Woo Ryu, Ji Hye Kim, Eui Ju Park, Woong Cheul Lee, Kwang Yeun Shim, Soung Won Jeong, Hyun Gun Kim, Tae Hee Lee, Sung Ran Jeon, Jun Hyung Cho, Joo Young Cho, Institution for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University Hospital, Seoul 140-743, South Korea
So Young Jin, Department of Pathology, Soonchunhyang University Hospital, Seoul 140-743, South Korea
Ji Sung Lee, Biostatistical Consulting Unit, Soonchunhyang University Hospital, Seoul 140-743, South Korea
Author contributions: Ham NS and Jang JY performed the majority of study; Jang JY performed the magnifying endoscopy and methylene blue chromoendoscopy and analyzed the results of the endoscopic examination; Ham NS collected the data and drafted the paper; Ryu SW, Kim JH, Park EJ, Lee WC and Shim KY organized the patients’ data; Jeong SW, Kim HG, Lee TH, Jeon SR, Cho JH and Cho JY consulted for our study; Jin SY analyzed the biopsies; and Lee JS helped with the statistical analysis.
Correspondence to: Jae Young Jang, MD, Institution for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University Hospital, 657 Hannam-dong, Yongsan-gu, Seoul 140-743, South Korea. jyjang@schmc.ac.kr
Telephone: +82-2-7099027 Fax: +82-2-7099696
Received: May 12, 2013
Revised: August 10, 2013
Accepted: September 13, 2013
Published online: November 7, 2013
Revised: August 10, 2013
Accepted: September 13, 2013
Published online: November 7, 2013
Core Tip
Core tip: Various endoscopic approaches and advancements have shown great promise. However, careful endoscopic observation and stepwise four quadrant biopsy still represent the standard for the surveillance of Barrett’s esophagus (BE). In our study, we investigated the usefulness of magnifying endoscopy for the diagnosis of specialized intestinal metaplasia (SIM) in patients with short-segment BE compared with methylene blue chromoendoscopy. We found that the magnified observation of a short-segment BE according to its mucosal pattern and classification can be predictive of SIM.