Bridging therapy and direct mechanical thrombectomy in the treatment of cardiogenic cerebral infarction with anterior circulation macrovascular occlusion

Table 1 Comparison of general information between the two groups

Group	n	Sex (Male/Female)	Age (year of age)	Combined with Diseases			Primary heart disease type			Time of onset to treatment (h)
				Hyperlipidemia	Hypertension	Diabetes mellitus	Heart valve disease	Myocardial infarction	Atrial fibrillation
Direct bolt group	48	26/22	67.35 ± 10.93	11	19	6	11	18	19	2.75 ± 1.09
Bridge therapy group	48	29/19	68.01 ± 11.33	13	22	4	13	19	16	2.90 ± 1.13
t/χ2 value		0.383	0.290	0.222	0.383	0.447	0.451			0.662
P value		0.536	0.772	0.637	0.536	0.504	0.798			0.510

Table 2 Comparison of treatment between the two groups (mean ± SD, min)

Group	Number	Time from admission to imaging examination	Time from admission to arterial puncture	Time from arterial puncture to vascular re-use	Time from admission to vascular re-use
Direct thrombectomy group	48	24.32 ± 8.61	95.56 ± 37.55	54.29 ± 21.38	156.88 ± 45.51
Bridging treatment group	48	25.38 ± 9.33	100.45 ± 39.30	58.14 ± 25.56	161.23 ± 51.15
t		0.578	0.623	0.800	0.440
P value		0.564	0.535	0.426	0.661

Table 3 Comparison of vascular recanalization between the two groups, n (%)

Group	n	Grade 0	Grade 1	Grade 2a	Grade 2b	Grade 3	Vascular recanalization
Direct thrombectomy group	48	2 (4.17)	3 (6.25)	5 (10.42)	18 (37.50)	20 (41.67)	38 (79.17)
Bridging treatment group	48	0 (0.00)	4 (8.33)	8 (16.67)	17 (35.42)	19 (39.58)	36 (75.00)
χ2							0.236
P value							0.627

Table 4 Comparison of National Institutes of Health Stroke Scale and Glasgow Coma Scale scores between the two groups (mean ± SD)

Group	n	NIHSS	GCS
Before treatment
Direct thrombectomy group	48	16.69 ± 4.91	12.12 ± 2.07
Bridging treatment group	48	18.01 ± 5.11	11.59 ± 1.98
t		1.290	1.282
P value		0.200	0.203
After treatment
Direct thrombectomy group	48	6.91 ± 1.10	14.19 ± 0.65
Bridging treatment group	48	7.13 ± 1.23	14.40 ± 0.59
t		0.924	1.657
P value		0.358	0.101

NIHSS: National Institutes of Health Stroke Scale; GCS: Glasgow Coma Scale.

Table 5 Comparison of prognostic effects between the two groups, n (%)

Group	n	0	1	2	3	4	5	6	Rate of good prognosis
Direct thrombectomy group	48	10 (20.83)	5 (10.42)	10 (20.83)	12 (25.00)	9 (18.75)	2 (4.17)	0 (0.00)	25 (52.08)
Bridging treatment group	48	11 (22.92)	6 (12.50)	7 (14.58)	13 (27.08)	7 (14.58)	3 (6.25)	1 (2.08)	24 (50.00)
χ2									0.042
P value									0.838