Retrospective Study
Copyright ©The Author(s) 2021.
World J Clin Cases. Jun 26, 2021; 9(18): 4627-4636
Published online Jun 26, 2021. doi: 10.12998/wjcc.v9.i18.4627
Table 1 Demographics characteristics of all participants
Characteristics
AD, n = 22
Control, n = 26
P value
Age (yr)74.7 ± 8.970.8 ± 8.50.121
Gender (female/male)11/1114/120.792
Education (yr)5.1 (4.6-11.2)6.2 (3.1-10.9)0.853
CDR (0/1/2/3)0/4/10/826/0/0/0-
MMSE13.6 ± 8.027.8 ± 1.5< 0.0011
Onset times (yr)3.8 (2.5-8.5)--
Table 2 Neuropsychiatric inventory score and psychological distress scores of caregivers
Case
NPI score, points
Item score, points
Psychological distress scores of caregivers, points
127Hallucination 6, irritability 12, sleep difficulties 910
224Hallucination 12, sleep difficulties 126
314Agitation 6, irritable 86
420Disinhibition 12, sleep difficulties 89
520Anxiety 8, indifference 126
624Agitation 12, irritable 128
712Hallucination 125
821Indifference 12, irritable 97
932Delusion 12, aggressive 8, sleep difficulties 1213
1012Depression 124
1120Delusion 12, irritable 89
1218Indifference 12, sleep difficulties 68
1312Indifference 124
Table 3 Mental symptoms of Alzheimer’s disease patients, n (%)
Symptoms
Total cases, n = 22
Mild AD, n = 4
Moderate AD, n = 10
Severe AD, n = 8
Irritability5 (22.73)1 (25)2 (20)2 (25)
Sleep difficulties5 (22.73)04 (40)1 (12.5)
Indifference4 (18.18)03 (30)1 (12.5)
Hallucination3 (13.64)02 (20)1 (12.5)
Agitation2 (9.09)1 (25)1 (10)0
Delusion2 (9.09)002 (25)
Disinhibition1 (4.55)001 (12.5)
Anxiety1 (4.55)01 (10)0
Aggressive1 (4.55)001 (12.5)
Depression1 (4.55)001 (12.5)
At least one of the above symptoms13 (59.1)1 (25)6 (60)6 (75)