Roles of exosomes in diagnosis and treatment of colorectal cancer

Table 1 Exosomes as prognostic and diagnostic biomarkers for colorectal cancer

Exosomes	Used samples	Expression	Function	Ref.
miR-23a, miR-301a	Serum	Increased	Diagnosis and prognosis	Karimi et al[86]
miR-193a, let-7g	Plasma	Increased, decreased	Diagnosis	Cho et al[87]
miR-548c-5p	Serum	Decreased	Diagnosis	Peng et al[88]
miR-92b	Plasma	Decreased	Diagnosis	Min et al[85]
miRNA-320d	Serum	Increased	Diagnosis	Tang et al[89]
let-7b-3p + miR-139-3p + miR-145-3p	Plasm	Increased	Diagnosis	Min et al[90]
miR-6803-5p	Serum	Increased	Diagnosis and prognosis	Yan et al[91]
miR-27a and miR-130a	Plasma	Increased	Diagnosis	Liu et al[92]
miR-122	Serum and cultured media	Increased	Diagnosis	Sun et al[80]
miR-150-5p + CEA	Serum	Decreased	Used for early diagnosis	Peng et al[88]
miR-99b-5p	Serum	Decreased	Diagnosis	Zhao et al[93]

CEA: Carcinoembryonic antigen.