Value of contrast-enhanced ultrasound combined with elastography in evaluating cervical lymph node metastasis in papillary thyroid carcinoma

Table 1 Comparison of general information between the metastatic group and reactive group

Group		Metastatic group (n = 50)	Reactive group (n = 63)	t/χ2	P
L/S ratio	> 2	24	60	32.606	0
	≤ 2	26	3
Boundary morphology	Irregular	36	7	43.13	0
	Regular	14	55
Liquefaction	Yes	2	0	-	0.113*
	No	48	63
Calcification	Yes	5	6	0.007	0.932
	No	45	57
Lymphatic portal	Yes	23	59	31.795	0
	No	27	4
Cortical echo	Low	35	53	3.229	0.072
	Qual/high	15	10
Blood flow distribution	Central type	26	53	13.678	0
	Peripheral or hybrid	24	10
Blood flow classification	0	6	6	2.914	0.233
	1	33	50
	2	11	7
PI		26.42 ± 6.79	21.82 ± 7.91	5.237	0
TP (s)		24.19 ± 4.37	24.32 ± 5.16	1.133	0.259
Area under curve		5.88 ± 1.57	5.73 ± 1.72	1.631	0.105
Contrast distribution	Non-uniform	24	10	13.678	0
	Uniform	26	53
No perfusion zone	Yes	4	2	-	0.140*
	No	46	61
Boundary	Unclear	8	9	0.064	0.8
	Clear	42	54
Elasticity score	1	0	33	31.795	0
	2	14	22
	3	23	8
	4	13	0
	5	0	0

^*Fisher's exact test. L/S: Long diameter/short diameter; PI: Peak intensity; TP: Time to peak.

Table 2 Multivariate regression analysis of cervical lymph node metastasis in papillary thyroid carcinoma patients

Factor	β	SE	Wald	P	OR	95.0%CI
						Lower limit	Upper limit
L/S (> 2 = 0, ≤ 2 = 1)	3.136	0.385	12.732	0.003	23.006	10.817	48.928
Boundary shape (rule = 0, irregular = 1)	0.767	0.681	3.294	0.134	2.153	0.567	8.179
Lymphatic portal (with = 0, no = 1)	2.796	0.582	13.592	0.002	16.384	5.236	51.266
Blood flow distribution (central type = 0, mixed type = 1)	0.093	0.209	1.563	0.329	1.098	0.729	1.654
PI	0.169	0.081	8.452	0.003	1.184	1.01	1.388
Contrast distribution (uniform = 0, non-uniform = 1)	0.453	0.301	3.73	0.065	1.573	0.872	2.838
Elasticity score	1.589	0.231	9.457	0.03	4.901	1.131	1.861