First platelet transfusion refractoriness in a patient with acute myelocytic leukemia: A case report

doi:10.12998/wjcc.v11.i29.7156

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Oct 16, 2023 (publication date) through May 17, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Oct 16, 2023; 11(29): 7156-7161
Published online Oct 16, 2023. doi: 10.12998/wjcc.v11.i29.7156

Table 1 Immune and nonimmune causes of platelet refractoriness

Nonimmune causes	Immune-mediated causes
Fever, infection, or sepsis	Antibodies against HLA class I
Bleeding	ABO-mismatched platelets
Accelerated platelet consumption (DIC, microangiopathic hemolytic anemia)	Antibodies against human platelet antigens
Drugs (amphotericin B, vancomycin, ATG, interferons)	Antibodies against drug–platelet glycoprotein complex
Splenic sequestration
Graft-versus-host disease
Poor platelet quality or greater storage age

DIC: Disseminated intravascular coagulation; ATG: Anti-human thymocyte globulin; HLA: Human leukocyte antigen; ABO: ABO blood group.

Citation: Tu SK, Fan HJ, Shi ZW, Li XL, Li M, Song K. First platelet transfusion refractoriness in a patient with acute myelocytic leukemia: A case report. World J Clin Cases 2023; 11(29): 7156-7161
URL: https://www.wjgnet.com/2307-8960/full/v11/i29/7156.htm
DOI: https://dx.doi.org/10.12998/wjcc.v11.i29.7156