Durable response to pulsatile icotinib for central nervous system metastases from EGFR-mutated non-small cell lung cancer: A case report

Figure 1 Baseline axial (A and B) and sagittal (C) T1w C+ craniocerebral magnetic resonance imaging showed the central nervous system metastases in the right frontal lobe (brain metastases and leptomeningeal metastases) and left cerebellar hemisphere (brain metastases) (white arrows).

Figure 2 Repeat axial (A and B) and sagittal (C) T1w C+ craniocerebral magnetic resonance imaging in August 2017 showed significantly enlarged lesions (white arrows).

Figure 3 Repeat axial (A and B) and sagittal (C) T1w C+ craniocerebral magnetic resonance imaging in May 2018 showed distinctly shrunken lesions (white arrows).

Figure 4 Repeat axial (A and B) and sagittal (C) repeat T1w C+ craniocerebral magnetic resonance imaging in September 2019 showed almost vanished lesions (white arrows).