Imaging of hemorrhagic primary central nervous system lymphoma: A case report

Figure 1 Brain computed tomography and magnetic resonance imaging showed a heterogeneous hyperintense signal in the right temporal lobe. A: Non-contrast-enhanced computed tomography images showed massive hemorrhage (orange star) with perilesional edema; B: The diffusion-weighted image (b = 1000 mm/s) demonstrates a relatively hyperintense signal of the parenchyma (orange arrow); C: T1-weighted image; D: T2W image showing the parenchyma (orange arrow) of the lesion as iso- to hypointense; E: Contrast-enhanced T1-weighted image revealed a ring-like enhancing pattern; and F: Arterial spin labeling showed relatively low perfusion of the whole lesion.

Figure 2 Histological examination and immunohistochemical analysis of the lesion. A: Hematoxylin-eosin staining revealed diffuse lymphoid cells with prominent nuclei; B, C: Immunohistochemistry analysis of the specimen shows positive staining of the cells for CD20 and Pax-5.