Incidence of infectious complications is associated with a high mortality in patients with hepatitis B virus-related acute-on-chronic liver failure

Figure 1 The recruitment and inclusion of patients with hepatitis B virus-related acute-on-chronic liver failure. ^aP < 0.05 compared with those without infections. HBV-ACLF: Hepatitis B virus-related acute-on-chronic liver failure; HAV: Hepatitis A virus; HCV: Hepatitis C virus; HEV: Hepatitis E virus; ACLF: Acute-on-chronic liver failure.

Figure 2 Receiver operating characteristic curve for assessing risk factors for bacterial and/or fungal infections in patients with hepatitis B virus-related acute-on-chronic liver failure. ROC: Receiver operating characteristic; HBV-ACLF: Hepatitis B virus-related acute-on-chronic liver failure; TBIL: Total bilirubin; PT: Prothrombin time; WBC: White blood cell; NE%: Percentage of neutrophils; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALB: Albumin.

Figure 3 Kinetics of serum total bilirubin and prothrombin time in hepatitis B virus-related acute-on-chronic liver failure patients during hospital stay. A and B: Serum total bilirubin (A) and prothrombin time (B) in hepatitis B virus-related acute-on-chronic liver failure patients at admission, week 1, week 2, and week 4. TBIL: Total bilirubin; PT: Prothrombin time.