Pulmonary Langerhans cell histiocytosis in adults: A case report

Figure 1 Findings from chest computed tomography scan at the lung window level from our patient. The characteristic nodulocystic pattern was detected at the time of pulmonary Langerhans cell histiocytosis diagnosis. A: Coronal scanning; B Cross-sectional scanning; C: Coronal scanning at 3 mo after smoking cessation, the lung nodulocystic lesions had disappeared significantly; and D: Cross-sectional scanning at 3 mo after smoking cessation, the lung nodulocystic lesions had disappeared significantly.

Figure 2 Findings from pathological analyses of lung biopsy from our patient. A: Haematoxylin-eosin staining showed a large number of typical Langerhans cells in the lung tissue, with abundant eosinophilic cytoplasm, irregular nuclei, and prominent folds and grooves; B: Langerhans cells showed positive staining for CD1a; C: Langerhans cells showed positive staining for S-100; D: Langerhans cells showed positive staining for CD68.