Huge primary dedifferentiated pancreatic liposarcoma mimicking carcinosarcoma in a young female: A case report

Figure 1 Preoperative computed tomography. Preoperative computed tomography shows a huge cystic-solid mass in the left upper abdomen, which compressed the superior mesenteric vein (Black arrow); necrosis can be seen in the mass (White arrow).

Figure 2 Surgical procedure. The pancreatic tail was removed. A: The giant mass in the pancreatic tail was approximately 28.0 cm × 19.0 cm × 8.0 cm. The black arrow shows the normal pancreatic tissue; B: The mass was longitudinally opened. The gray-white and fish-like incisal surface can be seen. The spleen is shown by the white arrow.

Figure 3 Histopathology. A: Coexisting areas of well-differentiated liposarcoma and the pancreatic canal (H and E × 100); B: Coexisting areas of dedifferentiated liposarcoma and the pancreatic canal (H and E × 100); C: Coexisting areas of well-differentiated liposarcoma and the pancreatic canal (H and E × 400); D: Coexisting areas of dedifferentiated liposarcoma and the pancreatic canal (H and E × 400). Blue arrows show areas containing the pancreatic canal. H and E: Hematoxylin and eosin.

Figure 4 Fluorescence in situ hybridization results. A: MDM2 gene amplification of the mass was positive (White arrow; as shown by three red dots and two green dots); B: MDM2 gene amplification of adjacent retroperitoneal tissue was negative (White arrow; as shown by two red dots and two green dots).