Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2019; 7(11): 1344-1350
Published online Jun 6, 2019. doi: 10.12998/wjcc.v7.i11.1344
Huge primary dedifferentiated pancreatic liposarcoma mimicking carcinosarcoma in a young female: A case report
Zhe Liu, Wu-Feng Fan, Gui-Chen Li, Jin Long, Yuan-Hong Xu, Gang Ma
Zhe Liu, Wu-Feng Fan, Gui-Chen Li, Jin Long, Yuan-Hong Xu, Gang Ma, Department of Pancreatic-Biliary Surgery, First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: All authors contributed to the acquisition of data and writing and revision of the manuscript.
Supported by the Liaoning Provincial Department of Education Science Research Project, No. L2014299; NSFC Molecular mechanism of aberrant expression of JDP2 and the regulation by JDP2 of TGF-beta-induced epithelial to mesenchymal transition in human pancreatic carcinoma, No. 81572360 (2016.1-2019.12).
Institutional review board statement: The study was performed retrospectively and was not antecedently reviewed by the Ethics Committee of China Medical University.
Informed consent statement: The patient involved in this study gave her written informed consent authorizing use and disclosure of her protected health information.
Conflict-of-interest statement: The authors declared that they have no conflicts of interest related to this work.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an inhouse editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BYNC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Gang Ma, MD, Assistant Professor, Department of Pancreatic-Biliary Surgery, First Hospital of China Medical University, Heping District, Nanjing Road No. 155, Shenyang 110001, Liaoning Province, China. liuzhecmu@126.com
Telephone: +86-024-83283330 Fax: +86-024-83283350
Received: December 28, 2018
Peer-review started: December 29, 2018
First decision: March 10, 2019
Revised: April 9, 2019
Accepted: May 1, 2019
Article in press: May 2, 2019
Published online: June 6, 2019
Core Tip

Core tip: Pancreatic liposarcoma is a rare tumor. We report a case of a 28-year-old female with a huge dedifferentiated liposarcoma in the pancreatic tail, 28.0 cm × 19.0 cm × 8.0 cm in size, with a yellow and white fish-like incisal surface. According to a literature review, this is the seventh case of pancreatic liposarcoma reported in the English literature and the third case of dedifferentiated liposarcoma. Furthermore, this case had the largest primary tumor volume, and a primary pancreatic liposarcoma was diagnosed based on sufficient evidence. The patient was treated with surgery but declined postoperative chemotherapy. She was well at the 26-mo follow-up, without relapse.